Presentation of the Column

This column will offer PhD students the opportunity to pursue research within memory processes and the most frequent neurodegenerative disorders: Alzheimer’s disease and related disorders, and α-synucleinopathies, including Parkinson’s disease, dementia with Lewy bodies, and multiple systems atrophy. These neurodegenerative disorders share common features: abnormal protein aggregation, mitochondrial dysfunction, neuroinflammation, and microvascular changes. The type and location of specific protein pathologies and other pathogenic factors may help to differentiate into separate underlying etiologies using biomarkers, incl. neuroimaging, genetic and biofluid markers. Early diagnosis is crucial for personalized counselling and pharmacological treatment (precision medicine). Currently, there are no disease-modifying treatments for these fatal disorders.

This column aims to understand the complex mechanistic interplay between the pathobiology specific for the disorder (e.g., amyloid, tau, α-synuclein) and pathogenic factors such as aging, inflammation, genetic susceptibility, microbiota and external triggering factors. Improved knowledge in these fields is crucial in order to develop more accessible diagnostic biomarkers, effective personalized treatments, and prevention strategies. Impairment of memory is key to many neurodegenerative disorders, and this column will also study various forms of memory processes spanning from episodic to declarative memory, as well as autobiographical memory, and from memory consolidation to memory extinction.

The Neurodegenerative Diseases research column offers a wide range of methodologies and resources bridging basic and clinical science, including epidemiological research, health data science, cell and animal models, in vivo and in vitro electrophysiology, circuit mapping, drug target validation, and state-of-the-art clinical neuroimaging and fluid biomarker studies of patients.

Speakers of Column

Gunhild Waldemar

Professor Gunhild Waldemar

Rigshospitalet - Copenhagen University HospitalDanish Dementia Research Center

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Per Borghammer

Professor Per Borghammer

Aarhus University Hospital

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Members of the column


Aalborg University

Associate Professor Maj Schneider Thomsen

Aalborg University • Department of Health Science and Technology • Neurobiology Research and Drug delivery

About the Research

Brain’s circulatory system and the handling of biometals in relation to neurodegenerative diseases. In vivo studies of TgSwDI mouse model of Alzheimer’s disease (AD) and in vitro construction of primary in vitro blood-brain barrier models.

Two lab members

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Lab rotation

Introduction to immunohistochemical staining, mouse brain anatomy, and microscopy. Hands-on with construction of in vitro blood-brain barrier models using rodent primary brain capillary endothelial cells, glial cells, and pericytes, data analysis.

Secondary Column

Brain Vasculature and Barriers

Professor Jakob Udby Blicher

Aalborg University Hospital • Department of Neurology •

About the Research

The research group focuses on clinical neurology. Students will be involved in clinical studies with active patient participation using techniques such as MRI, EEG and BCI technologies. The research group recently moved from CFIN, Aarhus University.

Two lab members

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Lab rotation

Secondary Column

Motor and Pain Neuroscience

Aarhus University

Professor Jørgen Kjems

Aarhus University • iNANO • Jørgen Kjems

About the Research

Therapeutic targeting of toxic aggregates, detecting a-Syn, role liposome fusion, PD biomarker discovery in CSF and blood, non-coding RNA in PD. Techniques: Aptamer selection, , super resolution microscopy, lipid vesicle fusion, RNA biomarkers and sp

Two lab members

Kirstine Jensen - PhD student
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Lab rotation

super resolution microscopy, real time visualization of single lipid vesicle fusion, characterization of RNA and protein biomarkers in CSF and blood, spatial transcriptomics in tissue

Secondary Column

Neurodevelopment

Associate Professor Simon Fristed Eskildsen

• Department of Clinical Medicine • CFIN

About the Research

Imaging biomarkers of neurodegenerative diseases for quantification of disease processes and prediction of disease progression. We work with MRI and PET and apply image processing and machine learning methods for modelling and prediction.

Two lab members

Lasse Madsen - PhD student

Mikkel Nygaard - PhD student

Lab rotation

Hands-on brain scanning, quantification from images, data analysis, relating imaging biomarkers to neuropsychology and clinical sympoms.

Secondary Column

Brain Vasculature and Barriers

Assistant Professor Nathalie  Van Den Berge

• Clinical Medicine • Van Den Berge lab

About the Research

My main focus is the investigation of the prion-like spreading of alpha-synuclein along the gut-brain axis in wild-type and transgenic animal models of Parkinson’s disease, and the influence of different risk-factors on disease progression.

Two lab members

Mie Kristine Just Pedersen - PhD student

Kristina Bang Kristensen - Lab technician

Lab rotation

hands-on in vivo experiments, including surgery and imaging; histology; LCO-assay; data-analysis

Secondary Column

Brain States and Brain-Body Interactions

Professor Hatice Tankisi

• Department of Clinical Neurophysiology • Tankisi

About the Research

Novel and conventional neurophysiological methods for the assessment of CNS and PNS, such as NCS, EMG, single fiber EMG, TMS, MUNE, nerve excitability testing with threshold tracking and muscle excitability testing.

Two lab members

Anna Bystrup Jacobsen - PhD student

Alexander Gramm Kristensen - Postdoc

Lab rotation

During the lab rotation, the upcoming PhD student will be introduced to the techniques. The student will learn theoretical background of the techniques and how to perform the examinations, and how to implement these in the disease of interest.

Secondary Column

Motor and Pain Neuroscience

Associate Professor Tomonori  Takeuchi

• Department of Biomedicine •

About the Research

The systems-level molecular mechanisms of selective retention of trivial everday memory through neuromodulation and the assimilation of this retained memory into the relevant knowledge structure called ”schema”.

Two lab members

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Lab rotation

Learning techniques (anatomical tract tracing, ex vivo two-photon imaging, optogenetics, fiber photometry imaging, behavioral tests on memory function) to answer a research question related to memory selectivity and knowledge updating.

Secondary Column

Associate Professor Taro  Kitazawa

• DANDRITE Nordic EMBL •

About the Research

Revealing epigenetic and transcriptional basis of neuroplasticity in memory engram cell formation by applying state of the art genomics technologies.

Two lab members

Valentina Khalil - Postdoc

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Lab rotation

Genomics (e.g. transcriptome, ChIP-seq, ATAC-seq, 3C-seq, single-cell), development of new genomics technologies, FACS isolation of TRAP labelled engram cells, photometry, histology, bioinformatics

Secondary Column

Associate Professor Heidi  Müller

• Department of Clinical Medicine • Müller group

About the Research

We investigate sortilin and APP regulation with particular focus on proteolytic processing and modulation by protein interaction partners. In addition, we are interested in molecular mechanisms facilitating rapid antidepressant actions.

Two lab members

Malene Overby - Postdoc

Tania Ammitzbøll - Lab technician

Lab rotation

Hands-on experience with techniques such as cell culturing, immunoblotting, protein-protein interaction assays, immunoprecipitation, biotinylation, cloning, BRET, subcellular fractionation methods and isolation and growth of primary neurons.

Secondary Column

Mood and Reward

Associate Professor Daniel Wüstner

• Biochemistry and Molecular Biology • Bioimaging section

About the Research

We are studying trafficking of proteins and lipids in neurodegenerative diseases. Main techniques used in the lab are quantitative live-cell fluorescence imaging, super-resolution and correlative microscopy combined with image analysis and AI.

Two lab members

Maria Szomek - Lab technician

Senjuti Halder - Postdoc

Lab rotation

wide field, confocal and super-resolution microscopy complemented by single particle tracking and diffusion analysis

Secondary Column

Brain Vasculature and Barriers

Associate Professor Andreas Nørgaard Glud

• Department of Neurosurgery • CENSE

About the Research

Large animal models of neurodegenerative diseases

Two lab members

Johannes Bech - PhD student

Dariusz Orlowski - Assistant Professor

Lab rotation

Hands on in large animal modeling

Secondary Column

Motor and Pain Neuroscience

Associate Professor Anne M Landau

• Clinical Medicine/Translational Research Unit and PET Center • Landau - Preclinical Neuroimaging

About the Research

PET imaging in vivo molecular changes in rodent and minipig models of Parkinson’s disease and depression. Molecular mechanisms related to neuroinflammation, synaptic density and epigenetics, and examination of the efficacy of putative therapies.

Two lab members

Majken B Thomsen - Postdoc

Karina Binda - PhD student

Lab rotation

Students will learn in vivo PET and postmortem autoradiography techniques. They will have the opportunity to participate in pilot microPET studies and/or conduct a small autoradiography study using brain sections from animal models

Secondary Column

Mood and Reward

Associate Professor Erik Lisbjerg Johnsen

Aarhus University Hospital • Neurology •

About the Research

Deep brain stimulation and perception for movement disorders

Two lab members

Mette Møller - Consultant

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Lab rotation

Human experiments, patient assessment, neurophysiology, brain-computer interface

Secondary Column

Associate Professor Hanne  Poulsen

• Molecular Biology and Genetics • MemBRAIN proteins

About the Research

Structure-function of neuronal membrane proteins

Two lab members

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Lab rotation

Electrophysiology, mouse work, basic molecular biology

Secondary Column

Associate Professor Marina  Romero-Ramos

• Department of Biomedicine •

About the Research

We investigate  a-synuclein induced neurodegeneration and immune associated response in Parkinson’s disease and evaluate therapeutic strategies. In our studies we use animal models and patients’ samples. Anatomy, FCAS, histology, behavior, scRNA

Two lab members

Sara Almeida Ferreira - Postdoc

Ida Klaestrup - PhD student

Lab rotation

Students will be introduced to: i) the immune response in synucleiopathies and how to analyze this in models and in patients; ii) disease modelling in rodents and how to use them to study neurodegeneration.

Secondary Column

Neuroinflammation and Neuron-Glia Interactions

Associate Professor Astrid Juhl Terkelsen

• Neurology, Aarhus University Hospital and Danish Pain Research Center, Aarhus University •

About the Research

Prodromal Parkinsonism with focus on small- and large fiber neuropathy and autonomic dysfunction using quantitative sudomotor axon reflex test, tilt table testing, Valsalva maneuver, deep respiration, 24-h BP, pupillometry, MIBG, and skin biopsies

Two lab members

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Lab rotation

Students will be involved in ongoing projects on prodromal parkinsons disease (PD), follow a consultant in the autonomic PD clinic, perform, evaluate and recognize errors/pitfalls in the autonomic tests.

Secondary Column

Motor and Pain Neuroscience

Associate Professor Yonglun  Luo

• Department of Biomedicine • DREAM

About the Research

My group is focusing on (1) better understanding the pathogenesis of neurodegenerative diseases by single cell and spatial multi-transcriptomics and (2) development of CRISPR-based gene therapy.

Two lab members

Camilla Blunk Brandt - PhD student

Yan Zhou - Postdoc

Lab rotation

Hands-on gene editing experiment, OMICS data analysis

Secondary Column

Brain Vasculature and Barriers

Professor Poul Henning Jensen

• Biomedicine & Dandrite • Neurodegenerative Diseases Laboratory

About the Research

The role of the protein -synucleins aggregation in neurodegenerative diseases using molecular, cellular, brain slice and mouse models and disease modifying strategies. Techniques: protein chem., aggregation & immuno assays, quantitative microscopy.

Two lab members

Hjalte Gram - PhD student

Nanna Møller Jensen - PhD student

Lab rotation

Hands-on protein aggregation, immuno-, biomarker-assays, cell culture and microscopy. Participation in Dandrite internal meetings and journal club

Secondary Column

Neurodegenerative Diseases

Professor Preben  Kidmose

• Dept. og Electrical and Computer Engineering • Center for Ear-EEG

About the Research

Wearable devices for long-term monitoring of neural activity (EEG and EMG) and other physiological measures (including respiratory, cardiovascular, and vocal tract activity). Machine learning algorithms.  Long-term EEG and polysomnography monitoring.

Two lab members

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Lab rotation

1) wearable EEG techniques (including ear-EEG) for out-patient monitoring; 2) Signal processing and machine learning methods for analysis of spontaneous EEG and sleep EEG recordings.

Secondary Column

Brain States and Brain-Body Interactions

Professor Per  Borghammer

Aarhus University Hospital • Department of Nuclear Medicine & PET • Borghammer group

About the Research

Parkinson’s disease (PD) research. Multi-modal imaging with PET, SPECT, and MR. Defining PD subtypes in longitudinal cohort studies using imaging. Characterizing non-motor symptoms. Animal models of PD, and neuropathology. Gut-brain interaction in PD

Two lab members

Nathalie Van Den Berge - Assistant Professor

Jacob Horsager - Postdoc

Lab rotation

Imaging analysis (PET, MRI, SPECT), possibly introduction to human experiments

Secondary Column

Professor Dorthe  Berntsen

• Department of Psychology and Behavioural Sciences •

About the Research

We study autobiographical memory (i.e., memory for the personal past) in healthy and disordered populations, including dementia, using a variety of methodologies, such as diary studies, survey studies, experiments, and neuropsychological assessments

Two lab members

Katrine Rasmussen - Postdoc

Alexander Kaiser - PhD student

Lab rotation

Cognitive psychological assessment, everyday memory research.

Secondary Column

Professor Daniel Erik Otzen

• iNANO • Otzen Biophysics group

About the Research

Molecular basis of α-synucleinopathies (particularly Parkinson’s) and therapeutic approaches against them using biophysical approaches. Mechanisms of α-syn aggregation and their inhibition by small molecules, peptides, nano- and antibodies.

Two lab members

Janni Nielsen - Lab technician

Marjan Omer - Postdoc

Lab rotation

Hands-on in vitro experiments and data analysis

Secondary Column

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Professor Poul  Nissen

• DANDRITE - Dept. Molecular Biology and Geetics • Nissen

About the Research

Structural biology of menbeane transporters and receptors in brain related to ion homeostasis/gradients (Na, K, Ca, Cl, pH), amino acids/neurotransmitters (dopamine, metabolism, insulin) and polarity/plasticity (BDNF, FRMD7)

Two lab members

Micael Habeck - Assistant Professor

Ronja Driller - Postdoc

Lab rotation

Studies into molecular mechanisms explaining mechanisms of genetic and circuit neurosciene

Secondary Column

Mood and Reward

Professor Sune Nørhøj Jespersen

• CFIN • Neurophysics

About the Research

Developing and applying methods for imaging brain microstructure with MRI

Two lab members

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Lab rotation

Participate in ongoing studies to learn about MRI, diffusion MRI, biophysical modeling, data analysis, simulation

Secondary Column

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University of Copenhagen

Professor Bjørn Hylsebeck Ebdrup

Mental Health Centre Glostrup • Centre for Neuropsychiatric Schizophrenia Research, CNSR •

About the Research

Focus on clinical neuropsychiatry. CNSR hosts the CINS database containing a broad range of data (including psychopathology, cognition, EEG, neuroimaging and genetics) primarily on never-medication patients with psychosis and schizophrenia.

Two lab members

Cecilie Lemvigh - Postdoc
Tina Kristensen - Postdoc

Lab rotation

psychopathology, cognition, EEG, neuroimaging (MRI, fMRI, DTI, MRS, PET/SPECT), machine learning

Secondary Column

Neurodevelopment

Associate Professor Lisbeth Marner

Copenhagen University Hospital Bispebjerg • Department of Clinical Physiology and Nuclear Medicine •

About the Research

Use of PET imaging for clinical diagnosis and disease progression in PD and MSA, and linking in-vivo functional measures to structure.

Two lab members

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Lab rotation

Students will learn about clinical and quantitative PET imaging in PD and MSA.

Secondary Column

Assistant Professor Ilary  Allodi

• Department of Neuroscience • Allodi laboratory

About the Research

Mouse models of Amyotrophic lateral sclerosis-Frontotemporal dementia, Behavioral assessment, Gene therapy, Multiplexing techniques: HiplexUP, RNAscope (ACD-Bio); Xenium (10X-Genomics), Spatial Transcriptomics: Nanostring GeoMX spatial profiling, Com

Two lab members

Santiago Mora - Postdoc

Anna Stuckert - Lab technician

Lab rotation

During lab rotation, the student will learn how to investigate motor and cognitive impairment in mouse models of ALS-FTD utilizing several behavioral paradigms, moreover, they will learn how to perform image analysis of behavior utilizing machine-lea

Secondary Column

Motor and Pain Neuroscience

Assistant Professor Niels Henning Skotte

• Department of Drug Design and Pharmacology • Skotte Group

About the Research

The focus of the Skotte Group is to explore protein alterations in Huntington’s disease to discover new biomarkers using human biofluids and to define novel drug targets using human induced pluripotent stem cells and murine single cell populations

Two lab members

Filippa Liliendahl Qvist - PhD student

Erika Bianca Torres Villanueva - Postdoc

Lab rotation

Primary murine CNS cells, IPSC culturing and differentiation, mouse experiments, human experiments, proteomics, and data analysis and visualisation, coding and use of Jupyter Notebook

Secondary Column

Neuroinflammation and Neuron-Glia Interactions

Assistant Professor Azadeh  Shahsavar

• Drug Design and Pharmacology •

About the Research

We aim to reveal the molecular details of glycine and glutamine transport using a multidisciplinary approach including structural studies by Cryo-EM and/or X-ray crystallography, and a range of biophysical and biochemical methods.

Two lab members

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Lab rotation

Secondary Column

Motor and Pain Neuroscience

Associate Professor Mattias  Rickhag

Danish Research Centre for Magnetic Resonance (DRCMR), Copenhagen University Hospital Hvidovre, Denmark • Danish Research Centre for Magnetic Resonance •

About the Research

Investigation of neuronal circuit function in rodents by use of viral tools (chemogenetic platforms). Viral platforms in combination with lesion models and neuroimaging to capture network/neurotransmitter changes in the cortico-basal ganglia circuit.

Two lab members

Nathalie Just - Assistant Professor

Mikkel Vinding - Assistant Professor

Lab rotation

Neuroanatomical connectivity, Neuronal circuit manipulation, Motor behavioral analysis (in rodents)

Secondary Column

Associate Professor Lisette  Salvesen

Bispebjerg Hospital • Department of Neurology •

About the Research

Linking clinical phenotypes in patients with motor neuron disease and atypical parkinsonism with clinical, biochemical, genetic, and neurophysiological biomarkers. Improvement of diagnosis, monitoring, and treatment.

Two lab members

Kirsten Svenstrup - Consultant, ph.d.

Sara Bech - Consultant, ph.d.

Lab rotation

Key techniques: Assessment of cognitive and motor function, with rating scales and diagnostic work up with molecular genetics, CSF, neurophysiological and imaging biomarkers.

Secondary Column

Associate Professor Julien  Ochala

• Biomedical sciences • Xlab

About the Research

Our research focuses on the understanding and treatment of neuromuscular diseases. We primarily use human tissue with techniques ranging from single molecule biophysics to muscle physiology and from advanced imaging to single cell proteomics.

Two lab members

Robert Seaborne - Postdoc

Jenni Laitila - Postdoc

Lab rotation

Handling human muscle tissue, being trained in single molecule assays, preparing cells for proteomics (LC/MS), analyzing big data

Secondary Column

Associate Professor Asmus  Vogel

University of Copenhagen • Department of Psychology • Danish Dementia Research Centre

About the Research

Cognitive dysfunction in dementia using neuropsychological testing

Two lab members

Rebecca Hendel - PhD student

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Lab rotation

experience with testing of memory and other cognitive functions

Secondary Column

Associate Professor Céline  Galvagnion-Büll

• Department of Drug Design and Pharmacology (ILF) • Protein-membrane interactions in health and disease

About the Research

We investigate how disruptions in lipid metabolism may lead to Parkinson’s Disease (PD) using biochemical, biophysical and omics methods to identify changes in lipid levels associated with PD and alpha-synuclein pathology in neurons and brain samples

Two lab members

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Lab rotation

biophysical characterisation of protein-membrane binding and protein aggregation; modelling PD risk factors in stem cells; isolation and characterisation of ex-vivo materials (e.g. LB); isolation and characterisation of lipids/organelles from neurons

Secondary Column

Associate Professor Annemette  Løkkegaard

Copenhagen University hospital Bispebjerg and frederiksberg • neurology •

About the Research

Improve symptomatic treatment of Parkinson’s disease, incl. advanced treatment and Deep Brain Stimulation. Cognitive changes and rehabilitation. Treatment effects and imaging. Linking clinical phenotypes with biochemical and neuroimaging biomarkers

Two lab members

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Lab rotation

Introduction to clinical research, clinical examination and ratings.

Secondary Column

Professor James B Rowe

University of Cambridge • Clinical Neurosciences •

About the Research

Systems cognitive neuroscience and its applications to dementia and parkinsonism. Multimodal integration and computational models of brain function. MEG, PET, MRI, neuropathology and drug trials.

Two lab members

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Lab rotation

Data acquisition, clinical obsevation if desired, data analysis, team discussion and methods learning for dementia experimental medicine

Secondary Column

Neuroinflammation and Neuron-Glia Interactions

Professor Ian  Law

Rigshospitalet • Dept clinical physiology, nuclear medicine and PET • Neuro

About the Research

Clinical PET and MRI on patients with neurodegenerative disorders, brain tumours, epilepsi and cerebrovascular disease. We have a subgroup using AI to process data. Our focus is on clinical implementation and diagnostic accuracy

Two lab members

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Lab rotation

Data processing of PET and MRI data

Secondary Column

Brain Vasculature and Barriers

Professor Carl-Johan  Boraxbekk

• Institute of Clinical Medicine/Danish Research center for Magnetic Resonance (DRCMR)/Institute of Sports Medicine •

About the Research

My group studies neural plasticity and improved brain function after interventions such as cognitive or physical training, by using multimodal brain imaging techniques including structural and functional MRI and PET and behavioral testing

Two lab members

Naiara Demnitz - Postdoc

David Meder - Postdoc

Lab rotation

Human experiments with MRI and/or PET; Longitudinal data analysis; Exercise and cognitive training interventions

Secondary Column

Brain States and Brain-Body Interactions

Professor Jette Sandholm Kastrup

• Department of Drug Design and Pharmacology • Receptor Structural Biology

About the Research

Structural biology on soluble and membrane proteins using crystallography and cryo-EM, with focus on ionotropic glutamate receptors and G protein-coupled receptors. Studies of protein-ligand interactions as basis for structure-based design.

Two lab members

Karla Frydenvang - Senior researcher

Heidi Peterson - Lab technician

Lab rotation

hands-on expression and purification of receptors, structure determination, structure analysis,

Secondary Column

Brain Vasculature and Barriers

Professor Gunhild  Waldemar

Copenhagen University Hospital, Rigshospitalet • Dept.of  Neurology • Danish Dementia Research Group

About the Research

Epidemiology of Alzheimer’s disease and other dementia disorders, risk factors, early symptoms and prognostic factors

Two lab members

Janet Janbek - Postdoc

Christina Jensen-Dahm - Postdoc

Lab rotation

planning of research based on health and quality registries, analysis and interpretation of data.

Secondary Column

Professor Shohreh  Issazadeh-Navikas

Biotech and Innovation Center (BRIC), Faculty of Health and Medical Sciences • BRIC • Neuroinflammation Unit, Issazadeh-Navikas group

About the Research

Research Interests Mitochondrial dysfunction and immunological mechanisms in PD and dementia 1. Role of immune gene defects in neuronal homeostasis 2. How immune genes control the function of mitochondria to prevent neuroinflammation & PDDpropagation

Two lab members

Emilie Tresse - Assistant Professor

Yawei Liu - Senior researcher

Lab rotation

Students will learn to utilize variety of techniques, using cellular (patient-derived, cell line or primary immune / neuronal cultures) and animal models of Parkinson´s disease dementia to address the molecular basis of the disease.

Secondary Column

Neuroinflammation and Neuron-Glia Interactions

Professor Jørgen Erik Nielsen

Rigshospitalet • Department of Neurology • Neurogenetics Clinic & Research Lab.

About the Research

Inherited neurodegenerative disorders (e.g. Huntington’s disease, Spinocerebellar ataxia type 2, CHMP2B-frontotemporal dementia); genotype/phenotype correlations; patient-derived iPSC neuronal models

Two lab members

Patrick Ejlerskov - Senior researcher

Anders Toft - PhD student

Lab rotation

Planning of research based on genotype/phenotype correlations, functional iPSC experiments, analyses and interpretation of data.

Secondary Column

Neuroinflammation and Neuron-Glia Interactions

Professor Søren  Brunak

• Novo Nordisk Foundation Center for Protein Research • Translational Disease Systems Biology

About the Research

Systems biology and health data integration in the brain disorder domain

Two lab members

Karina Banasik - Associate Professor

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Lab rotation

Secondary Column

Mood and Reward

Professor Steen Gregers Hasselbalch

Rigshospitalet • Danish Dementia Research Centre •

About the Research

Clinical research in diagnostic and prognostic biomarkers of neurodegenerative disorders, including biofluid and neuroimaging markers

Two lab members

Anja Hviid Simonsen - Senior researcher

Helena Gleerup - Master student

Lab rotation

Biomarker evaluation, data analysis of retrospective patient data

Secondary Column

University of Southern Denmark

Associate Professor Jette  Thuesen

• Department of Public Health • User Perspectives and Community Based Interventions

About the Research

Development and evaluation of community-based rehabilitation and palliative care interventions. Needs and experiences of people living with PD and/or Dementia in relation to public health services. Qualitative and survey methods, PPI-methods

Two lab members

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Lab rotation

User Involvement and users’ perspectives studies. Knowledge about (cognitive) rehabilitation and palliative care services in PD and Dementia.

Secondary Column

Professor Mojtaba Zarei

University Hospital Odense • Neurology • Danish Brain Mapping Centre

About the Research

Human Brain Mapping

Two lab members

Sasan Andalib - Senior researcher

Mohammad Taha Pourmohammad - PhD student

Lab rotation

Learning about various neuroimaging methids such as MRI, PET, MEG, EEG, TMS, etc

Secondary Column

Motor and Pain Neuroscience

Professor Morten  Meyer

• Department of Neurobiology Research, Institute of Molecular Medicine • Meyer Group

About the Research

Parkinsons’ disease pathogenesis (molecular and cellular mechanisms); identification of disease-modifying targets; role of neuron-glia interaction (stem cells; various biochemical, molecular and functional assays; bioimaging techniques).

Two lab members

Justyna Okarmus - Postdoc

Sissel Ida Schmidt - PhD student

Lab rotation

Students will work with induced pluripotent stem cell models of familial parkinson’s disease, derive neurons and astrocytes followed by molecular and functional analyses (phenotypic characterization).

Secondary Column

Neuroinflammation and Neuron-Glia Interactions

Professor Birgitte  Nørgaard

• Public Health • User perspectives

About the Research

User involvement and user perspectives, healthcare organization, communication, interprofessional collaboration, Patient Reported Outcomes (PRO) and Evidence Based Research

Two lab members

Michael Marcussen - Assistant Professor

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Lab rotation

Students will learn about user perspectives and user involvement in both clinical practice and in the research process, including methods for involving users and including the perspectives of relatives and informal caregivers

Secondary Column

University Hospitals

Associate Professor Tomasz Brudek

Bispebjerg-Frederiksberg Hospital • Centre for Neuroscience and Stereology •

About the Research

We think that impaired functioning of the immune system may be an important factor in neurodegeneration. We work with human material (Brains, plasma, PBMCs) and use different molecular biology technics, flow cytometry, cell cultures, IHC, MesoScale.

Two lab members

Jonas Folke - Postdoc

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Lab rotation

Hands on human and animal experiments employing different molecular techniques, microscopy and IHC.

Secondary Column

Neuroinflammation and Neuron-Glia Interactions

Associate Professor Susana Aznar

Bispebjerg and Frederiksberg Hospital • Department of Neurology • Center for Neuroscience and Stereology

About the Research

Mapping pathways sustaining neuroinflammation in synucleinopathies by i.a. omics- studies on human bio-samples and animal models, and how it links to disease progression. My aim is to identify appropriate biomarkers for immune interventions response

Two lab members

Anne_Line Strange Laursen - PhD student

Jonas Folke - Postdoc

Lab rotation

hands on Immuno- and histological techniques; gene/protein expression analysis; human brain tissue, shadowing a clinical examination; preclinical/in vitro studies

Secondary Column

Neuroinflammation and Neuron-Glia Interactions

Associate Professor Sanne Simone Kaalund

Bispebjerg Hospital • Neurology • Centre for Neuroscience and Stereology

About the Research

I study the structural and cellular pathology of neurodegenerative diseases in the human brain. I use quantitative (stereology) and semi-quantitative methods (automated imaged analysis) to map and track the spatiotemporal spreading of protein-aggrega

Two lab members

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Lab rotation

Hands-on histology and microscopy, image analysis, stereology, human brain tissue, shadowing a clinical examination

Secondary Column

Neuroinflammation and Neuron-Glia Interactions