NAD Fellow year: 2023

Alberte Wollesen Breum

MSc in Molecular Biomedicine, University of Copenhagen

PhD Project

Project title
To Sleep or Not to Sleep
PhD lab
Kornum Lab, Department of Neuroscience
University of Copenhagen
Main supervisor
Associate Professor Birgitte Kornum
Professor Gitte Moos Knudsen, Copenhagen University Hospitals - Rigshospitalet
Associate Professor Christoffer Clemmensen, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen

Lab rotations - pre-PhD year

Lab Rotation 1

Neurobiology Research Unit, Rigshospitalet

Alberte will do her first lab rotation with Clinical Professor Gitte Moos Knudsen of the Neurobiology Research Unit, Rigshospitalet, where she will focus on gaining experience within brain imaging on animals and humans and insight in clinical research.

Lab Rotation 2

Kornum Lab, Department of Neuroscience, University of Copenhagen

In the Kornum Lab, Alberte is integrated as a full member of the lab. She participates in all lab meetings and is introduced to all the ongoing projects. The group makes sure that there are some practical tasks for Alberte to perform in the lab and that she gets hands-on experience with the techniques needed for studying sleep in mice.

Lab Rotation 3

Stage Lab, University of Southern Denmark

Stage Lab focuses on translational research about the effect of drugs and why it varies between people. Alberte is integrated as a member of the group, she participates in all lab meetings, in the laboratory and is introduced to all the ongoing projects. Alberte takes part in a project looking into the role of Schwann cells in chemotherapy-induced peripheral neuropathy. She will will get hands-on experience with cell culture techniques and maintenance of iPSCs, and she will be working with differentiation of iPSC to Schwann cell precursors and Schwann cells, live cell imaging assay with chemotherapy exposure, qPCR, and immunostaining of mitochondria.

Meet Alberte Wollesen Breum

Alberte Wollesen Breum obtained her MSc in Molecular Biomedicine from the University of Copenhagen in 2021. Since then, she has been working as a research assistant in the Clemmensen Group at the Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen. The group works at the intersection between neuroscience and metabolism research, focusing on central regulation of food intake and energy expenditure.

Alberte characterises her neuroscience interest broadly as gaining an understanding of how the brain and the rest of the body interact. She loves basic research and the opportunities it provides for delving deeply into the mechanisms of the body.

After doing her bachelor’s and master’s thesis and working as a research assistant in the same lab, Alberte is excited to experience different research environments and learn new techniques, one of her main motivations for applying for an NAD fellowship:

“I am excited to go new places, get into deep waters and learn something new – and see how things are done in other labs.”

Alberte also highlights the opportunity to do a PhD with several supervisors: “Even though I can only choose one primary PhD lab, I can establish a connection with a co-supervisor and acquire contacts during my lab rotations.”